PASA: Proteomic analysis of serum antibodies web server
نویسندگان
چکیده
منابع مشابه
Proteomic Identification of Monoclonal Antibodies from Serum
Characterizing the in vivo dynamics of the polyclonal antibody repertoire in serum, such as that which might arise in response to stimulation with an antigen, is difficult due to the presence of many highly similar immunoglobulin proteins, each specified by distinct B lymphocytes. These challenges have precluded the use of conventional mass spectrometry for antibody identification based on pept...
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Plasma from different species is the most accessible and valuable source for biomarker discovery in clinical and animal samples. However, due to the high abundance of some proteins such as albumin and immunoglobulins, low-abundant proteins are often undetectable in proteomic analysis of plasma. We have established a plasma depletion scheme using chicken antibodies against various abundant prote...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2021
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1008607